NISA Otoño 2021
| Pos | Club | P | W | D | L | F | A | GD | Pts |
|---|---|---|---|---|---|---|---|---|---|
| 1 |  Detroit | 18 | 14 | 3 | 1 | 35 | 10 | 25 | 45 |
| 2 |  Strikers | 18 | 9 | 6 | 3 | 31 | 21 | 11 | 33 |
| 3 |  Force | 18 | 7 | 9 | 2 | 20 | 14 | 6 | 30 |
| 4 |  New Amsterdam | 18 | 7 | 2 | 9 | 29 | 29 | 0 | 23 |
| 5 |  Chattanooga | 18 | 7 | 2 | 9 | 20 | 21 | -1 | 23 |
| 6 |  Chicago House AC | 18 | 7 | 2 | 9 | 18 | 26 | -8 | 23 |
| 7 |  Michigan | 18 | 5 | 6 | 7 | 24 | 24 | 0 | 21 |
| 8 |  Stumptown | 18 | 4 | 8 | 6 | 13 | 18 | -5 | 20 |
| 9 |  Bobcats | 18 | 5 | 5 | 8 | 20 | 28 | -8 | 20 |
| 10 |  1904 FC | 18 | 2 | 3 | 13 | 17 | 37 | -20 | 9 |
